You can’t live without glutathione

You can’t live without glutathione

Health Benefits of glutathione

Have you ever heard of Glutathione?

Did you know it can save your life? 

As we age, our body’s ability to make this critical compound diminishes greatly, and until now there wasn’t an easy way to replace the glutathione we need. Now there is a revolutionary form of this crucial compound in a supplement form to get back to optimal levels — great news for anyone fighting Parkinson’s disease, Alzheimer’s, tumor progression and cancer growth and so much more.

Get to know Glutathione, now in a form you can use in this article from Terry Talks Nutrition.


There is no other compound quite like glutathione. It is so
important that your body makes its own supply to protect us from tumors, keep
DNA-damaging oxidative stress at bay, help the body rid itself of toxins, and
keep every cell rejuvenated and healthy. Unfortunately, our glutathione levels
tend to drop due to aging, genetics, disease, environment, and dozens of other
factors out of our control. Trying to boost glutathione levels with standard supplements
or N-acetylcysteine just doesn’t work. But a revolutionary form of this crucial
compound developed in France is powerful and effective. Taken daily, it will:

  • Prevent brain and nerve damage

  • Stop tumor progression and cancer growth

  • Rid you of health-threatening toxins

  • Protect you from DNA-damaging oxidative stress

  • Reduce the risk and slow the progression of
    Parkinson’s, Alzheimer’s, and other conditions

  • Promote longevity by protecting telomeres

  • Boost levels of active, protective glutathione

  • Improve the ratio of active versus oxidized

The Most Crucial of All Antioxidants, For the First Time
in a Form that Your Body Can Actually Use

What if I told you that Ponce de Leon was off base looking
for the Fountain of Youth in Florida, because that fountain is in your own
healthy liver? That may be a bit of a stretch, but your cells, especially in
your liver, make a master antioxidant and detox accelerator that controls
critical aspects of aging and preventing disease. That compound is called
glutathione. Virtually every person with disease-related frailty is depleted in
glutathione. High glutathione levels are associated with longevity – in fact;
healthy people over 100 years of age have significantly higher
levels of glutathione than the general population. There are over 90,000
studies published on different aspects of glutathione, on everything from
Parkinson’s disease, to cardiovascular damage, cancer treatment and prevention,
autoimmune diseases, even autism and related disorders. I could write the rest
of this page on diseases for which glutathione is crucial.

Unfortunately, in the presence of disease, environmental
exposures and genetics, our body’s ability to make this critical compound diminishes
greatly. With certain genetic inefficiencies, glutathione production can be
reduced 50% or more, and it is estimated that nearly 1 in 3 people has this
genetic variant! Age reduces glutathione production, too. By age 40, the
majority of people are making 30% less, and by 65, as much as 50% less – and
that is in healthy individuals. Anyone with liver stress or
disease is going to be making significantly less.

Since glutathione is so powerful, and the lack of adequate
levels is associated with too many diseases to count, why don’t we all just
load up on glutathione every day?

The answer is simple. Glutathione loses its super powers
with digestion. It becomes oxidized, and then it adds to your body’s oxidative
stress burden. It is not a matter of enteric coating, or stomach acid – it is
the digestive process itself that transforms glutathione into
its unfavorable form. That’s why elite, integrative medical clinics give this
life-saving compound intravenously (directly into the bloodstream), sometimes
at a cost of thousands of dollars to their patients.

Research scientists in France have developed a way to keep
glutathione stable and deliver it intact by combining glutathione with
protective antioxidants. This significantly improves the ratio of active glutathione
to oxidized glutathione in a way that other approaches can’t.

Fighting Free Radicals and Oxidative Stress

Glutathione has been described as “the mother of all
antioxidants” and this is true, but it does much more. It also boosts and
prolongs the protective activity of other antioxidants in the body, like
vitamin C and E. This is called antioxidant recycling, and it is crucial as we
strive to protect the blueprints inside our cells – DNA – from the damaging
effects of oxidative stress. This is important because unchecked oxidative
stress is associated with so many diseases – including cancers,
neurodegenerative diseases such as Parkinson’s and Alzheimer’s, and heart
disease – that it can aptly be considered a killer. Oxidative stress is
certainly involved in the death of damaged individual cells, and contributes
significantly to the progression of life-threatening diseases.

Removing Dangerous Toxins from the Body

As the liver snags toxins out of circulation, it must
prepare them for disposal. This process is called phase l and phase II
glucuronidation. This process cannot take place without adequate levels of
glutathione. More glutathione = enhanced removal of toxins from your body. This
can include drug metabolites, heavy metals, pesticides/herbicides,
xenoestrogens like BPA, alcohol, and other toxic chemicals. We are swimming in
a sea of tens of thousands of chemicals that never existed before 50 years ago.
While we cannot always avoid these toxic exposures, it is important to get them
out of our bodies as quickly as possible. This reduces our cumulative exposure
to substances linked to cancer and many other potentially devastating diseases.

Immune System Power

The foot soldiers of the immune system are white blood
cells. There are a wide variety of soldiers to help protect us from multiple
threats, such as disease-causing bacteria, viruses, and fungal infections. Your
body cannot make white blood cells without adequate glutathione. It has also
been shown to stimulate natural killer cell activity, which is especially
useful in destroying cancer cells.

Also, higher levels of glutathione are known to preserve
telomeres, which are the tail ends of genes that dictate how many times the
cell can regenerate. This process is intimately connected to longevity.

The Importance of Glutathione Ratios

Glutathione is made in the body from three amino acids:
glutamic acid, cysteine, and glycine. Glutathione molecules have their own
“life cycle.” As glutathione (GSH) is utilized and oxidized, it becomes
oxidized glutathione (GSSG). In a healthy, youthful person, 90% of the body’s
glutathione should be in the GSH form. This is also called “reduced
glutathione.” Only about 10% of the body’s glutathione should be in the GSSG
(oxidized) form. The ratio between these forms of glutathione is crucially
important and is a strong indication of health.

When glutathione is ingested in an unprotected form, meaning
it becomes oxidized before it is even absorbed, it contributes to the wrong
side of the equation! This increases the oxidative burden in the body because
of the excessive amounts of oxidized glutathione waiting to be recharged by
antioxidants. In this manner, oxidized glutathione actually depletes

Some practitioners use a precursor compound called
N-acetylcysteine (NAC). By increasing raw materials, they hope to make it
easier for the body to make more glutathione. This can be somewhat useful for
healthier people, because it is reliant on the strength of that individual’s
ability to make glutathione. Older adults and people with more serious, chronic
challenges are less fortunate, and some people have adverse effects with high
levels of NAC use.

Did you know that a specific form of glutathione has been
shown in human studies to boost the healthy ratio of active glutathione in the
body 65% better than NAC? And 230% better than unprotected glutathione! That
can mean a life-changing impact on health.

As for increasing levels of glutathione (GSH), this form was
compared to NAC and unprotected glutathione, and in just 11 days, raised levels
by 38 points. Unprotected glutathione decreased levels of the
active form by 40 points. That’s a 78 point difference between these groups,
which indicates this form of glutathione is more effective at increasing levels
of reduced glutathione.

Other delivery systems for glutathione have required 1,000
mg daily for six months to show effects. But because of the French process,
only 450 mg of glutathione daily boosted levels 38 points after only 11 days of
use, making it a powerful form of this nutrient.

Parkinson’s Disease

While glutathione is useful for virtually any disease or
health challenge, it is particularly useful for debilitating
neurological diseases like Parkinson’s disease (PD). There are studies using
intravenous (IV) glutathione that demonstrate its ability to improve
Parkinson’s symptoms. People with this chronic, progressive neurological
disorder have high levels of oxidative stress and premature cellular die off in
a part of the brain called the substantia nigra. Another hallmark of PD is the
loss of the brain’s ability to make dopamine. While more studies are needed to
further determine the ways in which glutathione helps PD, we have some solid
medical theories, the premise of which continues to be borne out as research

We know that glutathione reduces specific free radical
activity that interferes with the proper levels of both dopamine and
acetylcholine, which is believed to be the neurochemical imbalance underlying
Parkinson’s disease (PD).

As early as 1996, a study entitled “Reduced intravenous
glutathione in the treatment of early Parkinson’s disease” found that the
progression of PD was reduced, and symptoms improved by 42% after only 30 days
of treatment. However, the practice of using glutathione for PD was not
widespread, because it had to be administered directly into the veins (IV),
necessitating clinic visits and medical staff inserting needles for proper

In another 2009 study, Dr. David Perlmutter, a neurologist
at The Perlmutter Health Center, oversaw a human pilot study on the use of IV
glutathione for PD, the results of which he published in Movement
. The researchers reported significant improvement during one
month of glutathione treatment. When the treatments stopped, the symptoms
worsened again. Dr. Perlmutter’s group stated that glutathione was safe and
well tolerated.

Research on using therapeutic glutathione is incredibly
encouraging for this incurable neurological disease. The stumbling block has
always been that it has to be given IV, in a clinic licensed for administration
of intravenous drugs, in order to be effective. There are not many clinics
nationwide offering this service, and it is very expensive. It is truly a
medical break-through to be able to provide this glutathione in an oral form
that is still absorbed in its most effective form, without the need for
needles, clinics, and huge amounts of medical bills.


Cancer is a disease of improper cellular replication. Cell
DNA is damaged and the cell’s offspring no longer die on schedule. Oddly, when
our body makes immortal cells, our own mortality is in danger. This is the
origin of cancer. The immune system destroys cancer cells because it detects
this abnormality. However, when too many cancer cells are created, and/or our
immune system cannot keep up, we end up with cancer. Not all cancer is the same
– there are a myriad of causes and it can affect each person in a highly
differentiated manner.

One commonality, however, is that glutathione is useful for
the prevention of all cancers via a variety of mechanisms. By protecting the
DNA even from the harshest free radicals, our blueprints remain undamaged and
less likely to become cancerous cells. And by promoting rapid and effective
detoxification, glutathione greatly reduces our overall cellular exposure to
toxins, many of which are known carcinogens.

Researchers have explored how glutathione may be useful
during cancer treatment as well. In a 2008 study in Japan, doctors found that
using IV glutathione dramatically reduced nerve damage in patients being
treated with certain kinds of chemotherapy that cause neurotoxicity.

Because glutathione is so crucial to detoxification and
immune system vigor, many integrative practitioners use glutathione as part of
their clinical protocols for a wide variety of cancers.

Lyme Disease

Many health issues are made even more challenging by the
burden of free radicals. Consider the tick-borne Lyme disease, caused by
the Borrelia burgdorferi bacteria, which sometimes manifests
itself in “bullseye” pattern skin lesions, but can later progress to muscle
dysfunction, arthritis, facial palsy, and more. The body’s glutathione levels
are depleted in an effort to reduce the damage and spread of the disease.

However, antibiotic treatment doesn’t address the need for
the body to help heal itself. In fact, Polish researchers found that patients
using antibiotics to treat the skin lesion phase of the disease still had heavy
free-radical activity. Even though antibiotics in this case are standard
medical procedure, the resulting oxidative damage weakens the system.

This is why glutathione, because it replenishes the body’s
own levels, has become a standard practice in the integrative treatment of Lyme
disease. I believe it is good practice to bolster your glutathione ratio with
an oral form anytime you are going to spend extended time outdoors, or if you
live in a particularly tick-heavy environment during the spring, summer, and
fall months. If you already have Lyme disease, an oral form should help reduce
recurring flare-ups.

Rheumatoid Arthritis

Serbian researchers examined the relationship between
oxidative stress, free-radical activity, and rheumatoid arthritis (RA). Even
though patients with RA showed higher plasma levels of superoxide dismutase
(another of the body’s “super antioxidants”), they also had high levels of
pro-oxidants, and increased nitric oxide, an inflammatory marker. Other
research with RA patients in Italy showed a strong correlation between
inflammation, oxidative stress, and lowered glutathione levels in the
bloodstream. In fact, a clinical study in Jordan found that patients with RA
showed a 50% depletion of reduced glutathione compared to healthy controls. The
researchers concluded that “defense mechanisms against reactive oxygen species
are impaired in RA.” To me, this sounds like a strong reason for anyone with RA
to add active glutathione to their daily regimen.

Since rheumatoid arthritis is an autoimmune disease –
meaning the body is working against itself – many of the treatment options can
seem limited to pain reduction, rather than helping the body get its immune
balance back in shape. However, many current studies examining the relationship
between RA, oxidative stress, and inflammation seem to share the conclusion
that getting those factors under control is critical to stopping the arterial
stiffness and damage of the disease.

Autism and Autism Spectrum Disorders

The incidence of autism and related disorders has
skyrocketed in our modern, industrialized, toxin-laden world. Doctors have
known for quite a while that people with autism are especially challenged when
it comes to their ability to handle toxic exposures. Their detoxification
systems are rarely robust, and much of this has been traced to an insufficient
amount of glutathione activity.

A group of researchers performed a meta-analysis of studies
on aspects of autism as it relates to glutathione. They looked at the results
of 39 published studies, and determined there is significant evidence that two
specific pathways for detoxification are impaired in autism, and that large
trials are needed for children with autism to determine if boosting the
function of these two pathways will likewise improve autistic behaviors. Both
these pathways respond to improved ratios of active glutathione.

Alzheimer’s Disease

Virtually all neurological diseases have some level of
oxidative damage as a root cause or major contributor to dysfunction.
Therefore, it is not surprising that Alzheimer’s disease (AD) and mild
cognitive impairment (MCI) have been the focus of much glutathione research.

A recent study entitled “Elevation of glutathione as a
therapeutic strategy in Alzheimer’s disease” concludes: “Increasing glutathione
remains a promising therapeutic strategy to slow or prevent MCI and Alzheimer’s
disease.” Considering that glutathione levels continue to decline as we age,
and that both AD and MCI increase with age, supplementation with effective
glutathione can play an important role in prevention, or slowing the
progression of this disease.

Human Immunodeficiency Virus (HIV)

One hallmark of HIV is the inability of the immune system to
function properly. People with HIV often develop infections that can become
life-threatening, and one such infection is tuberculosis. Researchers extracted
immune system cells from people with HIV to see how well these cells would
control the mycobacterium that causes tuberculosis. They found that the
infection itself caused a depletion in glutathione, and that the immune cells,
in turn, could not control the mycobacteria. By boosting the body’s levels of
active glutathione, the cells could once again control the mycobacteria. The
researchers theorized that glutathione depletion may play at least a partial
causative role in reduced immune response in people with HIV, and that
increasing systemic glutathione could improve immune system function in this

Special Glutathione Challenges

Medications can also deplete your body of glutathione. One
is acetaminophen (one brand name is Tylenol). Acetaminophen is the number one
cause of acute liver failure in the U.S. and the only treatment for a dangerous
acetaminophen overdose is life-saving glutathione injected into the
bloodstream. Certain anti-seizure drugs deplete glutathione, and there is
evidence that birth control pills and antidepressant medication can also cause
depletion. Therefore, it is especially important to supplement with effective
glutathione if you must be on one or more of these drugs.

You Can’t Live Without Glutathione

Glutathione is absolutely necessary for health and vigor. In
fact, if you go 24 hours without food, your liver will steal amino acids from
the protein in your muscles to make this critical compound. I can’t promise you
the fountain of youth, but I can promise that you will live a longer,
healthier, more youthful life with optimal levels of glutathione.

Terry recommends taking 150 mg of the reduced, active
form of L-glutathione twice daily. If additional support is needed, increase to
150 mg three times daily.



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